anti-IL-6 antibody product blog
Tags: Antibody; IL-6; Monoclonal Antibody; anti-IL-6 antibody;
The IL-6 il6 (Catalog #MBS592338) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The mAb anti-Human IL-6 reacts with Human. Other species not tested and may cross-react with other species as described in the data sheet. MyBioSource\'s IL-6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA).ELISA: The antibody reacts with recombinant IL-6 antigen. Researchers should empirically determine the suitability of the IL-6 il6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IL-6 il6 product has the following accession number(s) (GI #124347) (NCBI Accession #P05231.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Description: Mouse monoclonal antibody to human interleukin-6 (IL-6)
background: IL-6, also called B-cell stimulatory factor-2 (BSF-2), is an important cytokine for the differentiation of B-cells into immunoglobulin-secreting cells. IL-6 is mainly produced by T-cells, macrophages and endothelial cells in response to pathogenic molecular stimuli during infection, trauma and the growth phase of some types of cancer. IL-6 is up-regulated by the binding of Toll-like receptors to antigen pattern ligands. In acute inflammatory phase, IL-6 causes increased body temperature by initiating synthesis of Prostaglandin E2 in hypothalamus.
Target Protein: Human IL-6
Immunogen: Purified recombinant human IL-6
Myeloma: F0
Light Chain: Kappa
Reconstitution: Double distillated water is recommended to reconstitute the antibody. Research Area: Cytokine, growth factor, inflammatory and autoimmune diseases. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IL-6 are readily searchable from our website. Different antibodies against the same target such as IL-6 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. IL-6 also interacts with the following gene(s): FOS, IL17A, IL1B, IL6R, IL6ST, JAK2, JUN, SOCS3, STAT1, STAT3. Blood, Bone, Brain, Connective Tissue, Eye, Kidney, Lung, Muscle, Skin, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene. Arthritis, Rheumatoid, Atherosclerosis, Autoimmune Diseases, Diabetes Mellitus, Type 2, Inflammation, Ischemia, Myocardial Ischemia, Necrosis, Obesity, Skin Diseases are some of the diseases may be linked to mAb anti-Human IL-6.