anti-IL13 antibody product blog
Tags: Antibody; Monoclonal Antibody; IL13; anti-IL13 antibody;
The IL13 il13 (Catalog #MBS834084) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s IL13 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS).FC: <= 0.25 ug/test
A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Researchers should empirically determine the suitability of the IL13 il13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IL13 il13 product has the following accession number(s) (GI #26787978) (NCBI Accession #NP_002179.2) (Uniprot Accession #P35225). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Rat monoclonal IL13 antibody (biotin).
Biological Significance: The 1316H antibody reacts with mouse IL-13. The 1316H antibody is a neutralizing antibody. Mouse interleukin-13, originally designated p600, is a 11.6 kDa protein secreted by activated T helper cells, CD8+ T cells, and NK cells. IL-13 was originally identified in 1989 through differential hybridization of cDNA libraries prepared from T helper 1 and T helper 2 cells. IL-13 contains four cysteine residues, which form two intramolecular disulfide bonds. IL-13 shares many activities with IL-4 this relates to a requirement for IL-4R alpha chain for signal transduction. The biological activities of IL-13 include suppression of macrophage cytotoxic activity, upregulation of IL-1RA expression, and suppression of inflammatory cytokine expression. IL-13 induces CD23 expression on B cells and enhances CD72, and expression of class II MHC gene products. Mouse IL-13 does not display the activities on T cells and B cell stimulatory effects which IL-4 exhibits. Mouse IL-13 is active on human and mouse cells. Tag/Conjugate: Biotin. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IL13 are readily searchable from our website. Different antibodies against the same target such as IL13 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. IL13 also interacts with the following gene(s): GATA3, IL13RA1, IL18, IL3, IL4R, IL5, STAT6, TSLP, VCAM1. Bone Marrow, Brain, Mixed, Testis tissues are correlated with this protein. The following patways have been known to be associated with this gene. Asthma, Bronchial Hyperreactivity, Dermatitis, Atopic, Fibrosis, Hypersensitivity, Hypersensitivity, Immediate, Inflammation, Lung Diseases, Necrosis, Respiratory Hypersensitivity are some of the diseases may be linked to IL13 antibody (biotin).