anti-IL13Ra2� antibody product blog
Tags: Antibody; Monoclonal Antibody; IL13Ra2�; anti-IL13Ra2� antibody;
The IL13Ra2� il13ra2 (Catalog #MBS2544454) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Mouse�IL13Ra2� Monoclonal Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s IL13Ra2� can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA).ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the IL13Ra2� il13ra2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IL13Ra2� il13ra2 product has the following accession number(s) (GI #10834992) (Uniprot Accession #O88786). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Interleukin-13 receptor subunit alpha-2 (IL13RA2/IL-13RA2) is also known as also known as cluster of differentiation 213A2 (CD213A2), IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, and IL-13RA2. The IL13RA2 is often overexpressed in brain tumors, making Il13ra2 one of the vaccine targets for immunotherapy of glioma. IL13RA2/IL-13RA2 is a cancer-associated receptor that is present in greater than 80% of High Grade Astrocytomas (HGA) and has recently been recognized as a cytokine that predisposes breast cancer cells to metastasize. Expression of IL13Ralpha2 was rapidly lost from the surface of transduced cells grown in culture. The loss appeared to be related to ligands present in fetal bovine serum in the medium. None of the malignant glioma cell lines cultivated in vitro and tested to date exhibited the IL13Ralpha2 receptor. A recombinant virus (R5111) enters cells via its interaction with the IL13Ralpha2 receptor in a manner that cannot be differentiated from the interaction of wild-type virus with its receptors.
Immunogen: Recombinant Mouse IL13RA2 protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IL13Ra2� are readily searchable from our website. Different antibodies against the same target such as IL13Ra2� may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adenocarcinoma, Anemia, Disease Models, Animal, Fibrosis, Hyperplasia, Hypertension, Inflammation, Lung Neoplasms, Necrosis, Skin Diseases are some of the diseases may be linked to Rabbit anti Mouse�IL13Ra2� Monoclonal Antibody.