|The Interleukin-like EMT inducer; FAM3C fam3c (Catalog #MBS565118) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ILEI monoclonal antibody (Delphy-1) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s ILEI can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB).
Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. Researchers should empirically determine the suitability of the Interleukin-like EMT inducer; FAM3C fam3c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Interleukin-like EMT inducer; FAM3C fam3c product has the following accession number(s) (GI #3334194) (NCBI Accession #Q92520.1) (Uniprot Accession #Q92520). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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In 2006, T. Waerner, et al. characterized ILEI as a key player in both epithelial to mesenchymal transition and late-stage carcinoma progression. EMT is a process that involves changes in gene expression, cytoskeleton organization, cell adhesion, and extracellular matrix composition. This process is important during tissue formation and organogenesis, but also during cancer progression, metastasis and chronic inflammation. ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors, an event strongly correlated to invasion/EMT, metastasis formation, and survival in human colon and breast cancer.
Source: Purified from concentrated hybridoma tissue culture supernatant
Immunogen: Recombinant human ILEI (aa 42-227). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Interleukin-like EMT inducer; FAM3C are readily searchable from our website. Different antibodies against the same target such as Interleukin-like EMT inducer; FAM3C may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Abnormalities, Multiple, Breast Neoplasms, Carcinoma, Fibrosis, Inflammation, Liver Diseases, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Skin Neoplasms are some of the diseases may be linked to ILEI monoclonal antibody (Delphy-1). Blood, Brain, Skin tissues are correlated with this protein.