|The ITGB1 itgb1 (Catalog #MBS609442) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Integrin, beta1 (CD29, Very Late Antigen, VLAb1, Platelet gplla) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Integrin, beta1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC).
Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin/paraffin): 1:15-1:30 for 60 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 1mM EDTA, pH 8.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Use of a high-sensitivity detection system may be required. Researchers should empirically determine the suitability of the ITGB1 itgb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ITGB1 itgb1 product has the following accession number(s) (GI #55959577) (Uniprot Accession #Q5T3E4). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
CD29 or the integrin B1 belongs to the family of cell adhesion receptors. It was initially characterized independently as protein gpIIa appearing on platelets, as the common b-subunit of the very late activation antigen (VLA) and as a component of various protein complexes binding to extracellular matrix proteins. CD29 is expressed at the cell surface exclusively as part of a heterodimer, in association with one of at least nine different integrin alpha subunits (alpha1-8; alpha V). With the exception of red blood cells and possible weak expression on granulocytes, CD29 is expressed in nearly all cell and tissue types.
Immunogen: Recombinant protein encoding the N-terminal region of human CD29. Cellular Localization: Cell membrane. MW of Antigen: 110kD (non-reducing) and 130kD (reducing). Positive Control: Tonsil. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ITGB1 are readily searchable from our website. Different antibodies against the same target such as ITGB1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. ITGB1 also interacts with the following gene(s): FN1, ITGA2, ITGA3, ITGA4, ITGA5, ITGA6, ITGA9, ITGAV, TLN1, VCAM1. Carcinoma, Cardiovascular Diseases, Disease Models, Animal, Fibrosis, Inflammation, Kidney Diseases, Neoplasm Invasiveness, Neoplasm Metastasis, Neoplasms, Nervous System Diseases are some of the diseases may be linked to Integrin, beta1 (CD29, Very Late Antigen, VLAb1, Platelet gplla).