anti-JNK antibody product blog
Tags: Antibody; Monoclonal Antibody; JNK; anti-JNK antibody;
The JNK1 mapk8 (Catalog #MBS2540206) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The JNK1 Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s JNK1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA).WB: 1:1000-1:10000
IHC: 1:20-1:200
IF: 1:20-1:200. Researchers should empirically determine the suitability of the JNK1 mapk8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The JNK1 mapk8 product has the following accession number(s) (GI #513788279) (NCBI Accession #NP_001265476.1) (Uniprot Accession #P45983). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the JNK1 Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of HEK-293 cells using JNK Monoclonal Antibody at dilution of 1:3000)
MAPK8(Mitogen-activated protein kinase 8) is also named as JNK1, PRKM8, SAPK1, SAPK1C and belongs to the MAP kinase subfamily. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. MAPK8 functions to phosphorylate c-Jun at N-terminal serine regulatory sites of Ser-63 and Ser-73, mapping within the transactivation domain. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun. It has 4 isoforms produced by alternative splicing with the molecular weight of 46 kDa and 48 kDa. This protein can be phosphorylated and this antibody recognizes the 46 kDa and 55 kDa bands in western blot.
Immunogen: Fusion protein of JNK. Buffer: PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation: Unconjugated. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing JNK1 are readily searchable from our website. Different antibodies against the same target such as JNK1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Brain Diseases, Cardiovascular Diseases, Disease Models, Animal, Drug Toxicity, Inflammation, Liver Diseases, Necrosis, Neoplasms, Nervous System Diseases, Reperfusion Injury are some of the diseases may be linked to JNK1 Monoclonal Antibody. Blood, Bone, Brain, Connective Tissue, Heart, Kidney, Lung, Prostate, Skin, Vascular tissues are correlated with this protein.