anti-KARS antibody product blog
Tags: Antibody; KARS; Monoclonal Antibody; anti-Kars antibody;
The KARS kars (Catalog #MBS246188) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone 8G12C1] (IgG1) to Human KARS reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s KARS can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA).ELISA (1:10000), IHC-P (1:200), WB (1:500 - 1:2000). Researchers should empirically determine the suitability of the KARS kars for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The KARS kars product has the following accession number(s) (GI #5031815) (NCBI Accession #NP_005539.1) (Uniprot Accession #Q15046). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Mouse Monoclonal [clone 8G12C1] (IgG1) to Human KARS with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-KARS antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.)
Immunohistochemistry (IHC) (Anti-KARS antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.)
Western Blot (WB) (Western blot of anti-KARS monoclonal antibody against truncated Trx-KARS recombinant protein(1), truncated MBP-KARS(aa90-174) and full length KARS(aa1-188) transfected CHO-K1 cell lysate(3).)
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
Target Species: Human
Immunogen Description: Purified recombinant fragment of KARS(aa90-174) expressed in E Coli. Immunogen: KARS antibody was raised against purified recombinant fragment of KARS(aa90-174) expressed in E Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KARS are readily searchable from our website. Different antibodies against the same target such as KARS may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Heart, Kidney, Liver, Lung, Muscle, Nerve, Vascular tissues are correlated with this protein.