|The KCNJ10 kcnj10 (Catalog #MBS6004229) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The KCNJ10 (ATP-sensitive Inward Rectifier Potassium Channel 10, ATP-dependent Inwardly Rectifying Potassium Channel Kir4.1, Inward Rectifier K(+) Channel Kir1.2, Potassium Channel, Inwardly Rectifying Subfamily J Member 10) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s KCNJ10 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the KCNJ10 kcnj10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The KCNJ10 kcnj10 product has the following accession number(s) (GI #126153403) (NCBI Accession #AAI31628.1) (Uniprot Accession #P78508). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
DFELVLILSG TVESTSATCQ VRTSYLPEEI LWGYEFTPAI SLSASGKYIA DFSLFDQVVK VASPSGLRDS TVRYGDPEKL KLEESLREQA EKEGSALSVR ISNV.
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This gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes.
Immunogen: Partial recombinant corresponding to aa276-379 rom human KCNJ10 (NP_002232) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KCNJ10 are readily searchable from our website. Different antibodies against the same target such as KCNJ10 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. KCNJ10 also interacts with the following gene(s): AQP4, KCNJ16, SLC26A4. Blood, Brain, Ear, Eye, Ganglia, Kidney, Nerve, Spleen tissues are correlated with this protein. The following patways have been known to be associated with this gene. Atrophy, Hypertrophy, Inflammation, Kidney Diseases, Neoplasms, Neoplasms, Experimental, Nerve Degeneration, Nervous System Malformations, Pneumonia, SEIZURES, SENSORINEURAL DEAFNESS, ATAXIA, MENTAL RETARDATION, AND ELECTROLYTE IMBALANCE are some of the diseases may be linked to KCNJ10 (ATP-sensitive Inward Rectifier Potassium Channel 10, ATP-dependent Inwardly Rectifying Potassium Channel Kir4.1, Inward Rectifier K(+) Channel Kir1.2, Potassium Channel, Inwardly Rectifying Subfamily J Member 10).