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anti-Kcnmb2 antibody product blog

Posted on 2016-02-20 14:55:26 by mybiosource_staff
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Tags: Antibody; Monoclonal Antibody; BK Beta2; anti-Kcnmb2 antibody; Kcnmb2;
The Kcnmb2 kcnmb2 (Catalog #MBS801295) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The BK Beta2 Antibody: HRP reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s BK Beta2 can be used in a range of immunoassay formats including, but not limited to, Western (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP).
1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF). Researchers should empirically determine the suitability of the Kcnmb2 kcnmb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The Kcnmb2 kcnmb2 product has the following accession number(s) (GI #21312300) (NCBI Accession #NP_082507.1) (Uniprot Accession #Q9CZM9). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the BK Beta2 Antibody: HRP with the following immunoassay(s):
Testing Data (Western blot analysis of BK Beta2 in a human cell line mix using a 1:1000 dilution.)
Testing Data Kcnmb2.

Background Info: No cross-reactivity against BKBeta1, BKBeta3 or BKBeta4.

Scientific Background: BK channels contribute to electrical impulses, proper signal transmission of information and regulation of neurotransmitter release (3). A gain of function mutation in the pore-forming alpha subunit of the BK channel was linked to human neurological diseases. Findings suggest that the distribution of the beta subunits in the brain can modulate the BK channels to contribute to the pathophysiology of epilepsy and dyskinesia (4). This has major implications on other physiological processes in tissues other than the brain.

Conjugate: HRP. Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Kcnmb2 are readily searchable from our website. Different antibodies against the same target such as Kcnmb2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Fibrosis are some of the diseases may be linked to BK Beta2 Antibody: HRP. Brain, Eye tissues are correlated with this protein. The following patways have been known to be associated with this gene.
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