anti-KIF22 antibody product blog
Tags: Antibody; Monoclonal Antibody; KIF22; anti-KIF22 antibody;
The KIF22 kif22 (Catalog #MBS476220) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-KIF22 Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s KIF22 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the KIF22 kif22 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The KIF22 kif22 product has the following accession number(s) (GI #372266146) (NCBI Accession #NP_001243198.1) (Uniprot Accession #Q14807). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-KIF22 Mouse mAb with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts from MCF7 and Hela cell lysates using KIF22 mouse mAb (1:1000 diluted).Predicted band size:73KDa.Observed band size:73KDa.)
Western Blot (WB) (Western blot analysis using KID mouse mAb against MCF-7 (1) and Hela (2) cell lysate.)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using KID mouse mAb with DAB staining.)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using KID mouse mAb with DAB staining.)
Entrez Summary: The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
UniPort Summary Function: Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA (By similarity). Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells (PubMed:25743205).
Immunogen: Purified recombinant fragment of human KID expressed in E Coli.
Sequence Similarities: Contains 1 kinesin motor domain. Subunit Structure: Interacts with FAM83D (PubMed:18485706). Interacts with SIAH1 (PubMed:11146551).
Subcellular Location: Cytoplasm; Cytoskeleton. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KIF22 are readily searchable from our website. Different antibodies against the same target such as KIF22 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.