anti-KIR2DL1 antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-KIR2DL1 antibody; KIR2DL1;
The KIR2DL1 kir2dl1 (Catalog #MBS690270) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Human KIR2DL1 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s KIR2DL1 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the KIR2DL1 kir2dl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The KIR2DL1 kir2dl1 product has the following accession number(s) (GI #110611923) (NCBI Accession #NP_055033.2) (Uniprot Accession #P43626). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
The KIR gene family currently consists of 15 gene loci (KIR2DL1, KIR2DL2/L3, KIR2DL4, KIR2DL5A, KIR2DL5B, KIR2DS1, KIR2DS2, KIR2DS3, KIR2DS4, KIR2DS5, KIR3DL1/S1, KIR3DL2, KIR3DL3 and two pseudogenes, KIR2DP1 and KIR3DP1) encoded within a 100-200 Kb region of the Leukocyte Receptor Complex (LRC) located on chromosome 19 (19q13.4). The LRC constitutes a large, 1 Mb, and dense cluster of rapidly evolving immune genes which contains genes encoding other cell surface molecules with distinctive Ig-like extra-cellular domains. These genes include, from centromere to telomere, Leukocyte Immunoglobulin-like Receptors (LILR) and Leukocyte-Associated Immunoglobulin-like Receptors (LAIR), FcGammaR as well as the Natural cytotoxicity-triggering Receptor 1 (NCR1). In addition the extended LRC contains genes encoding the Sialic acid binding Immunoglobulin-like Lectins (SIGLEC) and the CD66 family members such as the carcino-embryonic antigen (CEA) genes as well as the genes encoding the transmembrane adaptor molecules DAP10 and DAP12.
Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of KIR2DL1. Reconstitution: Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KIR2DL1 are readily searchable from our website. Different antibodies against the same target such as KIR2DL1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.