|The KLK3 n/a (Catalog #MBS476308) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-KLK3 Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s KLK3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the KLK3 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The KLK3 n/a product has the following accession number(s) (GI #57114133) (NCBI Accession #NP_001009136.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-KLK3 Mouse mAb with the following immunoassay(s):
Western Blot (WB) (Western blot analysis using KLK3 mAb against human KLK3 (AA)
Flow Cytometry (FC/FACS) (Flow cytometric analysis of HeLa cells using KLK3 mouse mAb (green) and negative control (red).)
Entrez Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
Immunogen: Purified recombinant fragment of human KLK3 expressed in E Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KLK3 are readily searchable from our website. Different antibodies against the same target such as KLK3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.