anti-KLK8 antibody product blog
Tags: Antibody; KLK8; Monoclonal Antibody; anti-KLK8 antibody;
The KLK8 klk8 (Catalog #MBS646056) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The KLK8 (Kallikrein-8, hK8, Neuropsin, NP, Ovasin, Serine Protease 19, Serine Protease TADG-14, Tumor-associated Differentially Expressed Gene 14 Protein, NRPN, PRSS19, TADG14, UNQ283/PRO322) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s KLK8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF).Suitable for use in Immunofluorescence, ELISA and Western Blot.
Dilution: Immunofluorescence: 10ug/ml. Researchers should empirically determine the suitability of the KLK8 klk8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The KLK8 klk8 product has the following accession number(s) (GI #21464131) (NCBI Accession #NP_653090.1) (Uniprot Accession #O60259). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
EIPVVQSIPH PCYNSSDVED HNHDLMLLQL RDQASLGSKV KPISLADHCT QPGQKCTVSG WGTVTSPREN FPDTLNCAEV KIFPQKKCED AYPGQITDGM VCAGSSKG*.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the KLK8 (Kallikrein-8, hK8, Neuropsin, NP, Ovasin, Serine Protease 19, Serine Protease TADG-14, Tumor-associated Differentially Expressed Gene 14 Protein, NRPN, PRSS19, TADG14, UNQ283/PRO322) with the following immunoassay(s):
Western Blot (WB) (Western Blot detection against Immunogen (37.99kD) using MBS646056.)
Western Blot (WB) (Western Blot analysis of KLK8 expression in A-431 using MBS646056.)
Immunofluorescence (IF) (Immunofluorescence of MBS646056 on A-431 cell. [antibody concentration 10ug/ml])
Testing Data (Detection limit for recombinant GST tagged KLK8 is ~0.3ng/ml as a capture antibody.)
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer.
Immunogen: Partial recombinant corresponding to aa97-205 from KLK8 (NP_009127) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KLK8 are readily searchable from our website. Different antibodies against the same target such as KLK8 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.