|The KRT8 krt8 (Catalog #MBS530901) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Cytokeratin 8 antibody (biotin) reacts with Hamster, Human, Mouse, Opossum, Rat, Treeshrew and may cross-react with other species as described in the data sheet. MyBioSource\'s Cytokeratin 8 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB).
IHC-P: 1:10. Researchers should empirically determine the suitability of the KRT8 krt8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The KRT8 krt8 product has the following accession number(s) (GI #181573) (NCBI Accession #AAA35763.1) (Uniprot Accession #P05787). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Mouse monoclonal Cytokeratin 8 antibody (biotin).
Biological Significance: Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Keratin, type I cytoskeletal 8 also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that in human is encoded by the KRT8 gene. It is often paired with keratin 18. Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen: Cytokeratin 8 antibody (biotin) was raised in mouse using cytoskeletal proteins from cultured HeLa Cells as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KRT8 are readily searchable from our website. Different antibodies against the same target such as KRT8 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bone, Embryonic Tissue, Kidney, Liver, Lung, Lymph, Lymph Node, Mouth, Prostate, Skin tissues are correlated with this protein. The following patways have been known to be associated with this gene. Adenocarcinoma, Breast Neoplasms, Disease Models, Animal, Fibrosis, Inflammation, Liver Cirrhosis, Liver Diseases, Liver Neoplasms, Necrosis, Neoplasm Metastasis are some of the diseases may be linked to Cytokeratin 8 antibody (biotin).