anti-LIN7B antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-LIN7B antibody; LIN7B;
The LIN7B lin7b (Catalog #MBS834737) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s LIN7B can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB).FC: 1:100
IF: 1:100
IHC: 1:150
WB: 1:2000. Researchers should empirically determine the suitability of the LIN7B lin7b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The LIN7B lin7b product has the following accession number(s) (GI #11545920) (NCBI Accession #NP_071448) (Uniprot Accession #Q9HAP6). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the LIN7B antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant LIN7B protein (Right) or empty vector (Left) detected with LIN7B antibody)
Immunohistochemistry (IHC) (Immunohistochemical analysis of LIN7B protein in paraffin embedded Carcinoma of Human bladder tissue using LIN7B antibody)
Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant LIN7B protein using LIN7B antibody)
Mouse monoclonal LIN7B antibody.
Biological Significance: LIN7B plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. it forms membrane-associated multiprotein complexes that may regulate delivery andrecycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B orLIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensuresthe proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may functionin localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Cross-Reactivity: Human
Immunogen: LIN7B antibody was raised in mouse using a full length recombinant protein of human LIN7B (NP_071448) produced in HEK293T cells, as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing LIN7B are readily searchable from our website. Different antibodies against the same target such as LIN7B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.