|The LLGL1 llgl1 (Catalog #MBS6003877) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The LLGL1 (Lethal(2) Giant Larvae Protein Homolog 1, LLGL, Human Homolog To The D-lgl Gene Protein, Hugl-1, DLG4, DLG4, HUGL, HUGL1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s LLGL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the LLGL1 llgl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The LLGL1 llgl1 product has the following accession number(s) (GI #62912476) (NCBI Accession #NP_004131.3) (Uniprot Accession #Q15334). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
GIASCVFTRH GQGFYLISPS EFERFSLSAR NITEPLCSLD INWPRDATQA SYRIRESPKL SQANGTPSIL LAPQSLDGSP DPAHSMGPDT PEPPEAALSP.
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Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Involved in axonogenesis through RAB10 activation thereby regulating vesicular membrane trafficking toward the axonal plasma membrane.
Immunogen: Partial recombinant corresponding to aa911-1010 from human LLGL1 (NP_004131) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing LLGL1 are readily searchable from our website. Different antibodies against the same target such as LLGL1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Carcinoma, Hepatocellular, Carcinoma, Renal Cell, Kidney Diseases, Liver Diseases, Liver Neoplasms, Liver Neoplasms, Experimental, Neoplasm Metastasis, Neoplasms, Neurobehavioral Manifestations, Neurologic Manifestations are some of the diseases may be linked to LLGL1 (Lethal(2) Giant Larvae Protein Homolog 1, LLGL, Human Homolog To The D-lgl Gene Protein, Hugl-1, DLG4, DLG4, HUGL, HUGL1). LLGL1 also interacts with the following gene(s): FLII. Brain, Embryonic Tissue, Eye, Heart, Intestine, Kidney, Lung, Lymph Node, Mammary Gland, Uncharacterized Tissue tissues are correlated with this protein.