anti-LOX antibody product blog
Tags: Antibody; LOX; Monoclonal Antibody; anti-LOX antibody;
The LOX lox (Catalog #MBS833428) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s LOX can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF).FC: 1:100
IF: 1:100. Researchers should empirically determine the suitability of the LOX lox for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The LOX lox product has the following accession number(s) (GI #20149540) (NCBI Accession #NP_002308) (Uniprot Accession #P28300). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the LOX antibody with the following immunoassay(s):
Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant LOX protein using LOX antibody)
Mouse monoclonal LOX antibody.
Biological Significance: LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, The encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutislaxa type I (CL type I). Cross-Reactivity: Human
Immunogen: LOX antibody was raised in mouse using a human recombinant protein fragment corresponding to amino acids 22-168 of human LOX (NP_002308) produced in HEK293T cells, as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing LOX are readily searchable from our website. Different antibodies against the same target such as LOX may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain Diseases, Cardiovascular Diseases, Disease Models, Animal, Fibrosis, Heart Diseases, Hypertension, Inflammation, Lung Neoplasms, Necrosis, Neoplasms, Experimental are some of the diseases may be linked to LOX antibody. LOX also interacts with the following gene(s): BMP1, FBLN5, FGF2, LOXL1, SNAI1, SRC. Bone, Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Muscle, Skin, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene.