anti-LPAR1 antibody product blog
Tags: Antibody; LPAR1; Monoclonal Antibody; anti-Lpar1 antibody;
The LPAR1 lpar1 (Catalog #MBS834857) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s LPAR1 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Western Blot (WB).FC: 1:100
WB: 1:2000. Researchers should empirically determine the suitability of the LPAR1 lpar1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The LPAR1 lpar1 product has the following accession number(s) (GI #16950636) (NCBI Accession #NP_001392) (Uniprot Accession #Q92633). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the LPAR1 antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant LPAR1 protein (Right) or empty vector (Left) detected with LPAR1 antibody)
Mouse monoclonal LPAR1 antibody.
Biological Significance: The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cellsignaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Cross-Reactivity: Human
Immunogen: LPAR1 antibody was raised in mouse using a full length recombinant protein of human LPAR1 (NP_001392) produced in HEK293T cells, as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing LPAR1 are readily searchable from our website. Different antibodies against the same target such as LPAR1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bone, Bone Marrow, Heart, Liver, Lung, Nerve, Placenta, Skin, Uterus, Vascular tissues are correlated with this protein. Adenocarcinoma, Disease Models, Animal, Fibrosis, Hypertension, Inflammation, Liver Diseases, Liver Neoplasms, Lung Neoplasms, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to LPAR1 antibody. The following patways have been known to be associated with this gene. LPAR1 also interacts with the following gene(s): LPAR4, LPAR5, LPAR6.