|The LRP1 lrp1 (Catalog #MBS633622) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Lipoprotein Receptor-related Protein, Low Density (LRP, Alpha 2 Macroglobulin Receptor, A2MR, Apolipoprotein E Receptor, APOER, APR, CD91, Low Density Lipoprotein Receptor Related Protein 1, LRP1, LRP-1) (PE) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Lipoprotein Receptor-related Protein, Low Density can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS).
Suitable for use in Flow Cytometry.
Dilution: Flow Cytometry: Neat, 10ul labels 10e6 cells in 100ul. Researchers should empirically determine the suitability of the LRP1 lrp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The LRP1 lrp1 product has the following accession number(s) (GI #3493576) (Uniprot Accession #Q07954). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Lipoprotein Receptor-related Protein, Low Density (LRP, Alpha 2 Macroglobulin Receptor, A2MR, Apolipoprotein E Receptor, APOER, APR, CD91, Low Density Lipoprotein Receptor Related Protein 1, LRP1, LRP-1) (PE)
Low density lipoprotein (LDL) receptor-related protein (LRP), a member of the LDL receptor family, binds multiple classes of ligands and has been implicated in a broad range of normal and disease processes involving lipid metabolism, protease clearance, and cell migration. Structurally, members of the LDLR family share homology within their extracellular domains, which are highlighted by the presence of clusters of ligand-binding repeats. LRP is a large endocytic receptor that participates in several biological pathways and plays prominent roles in lipoprotein metabolism and in the catabolism of proteinases involved in coagulation and fibrinolysis. LRP also mediates the cellular entry of certain viruses and toxins and facilitates the activation of various lysosomal enzymes. All LRPs are expressed in the central nervous system and, for most receptors, animal models have shown that they are indispensable for successful neurodevelopment. The mechanisms by which they regulate the formation of the nervous system are varied and include the transduction of extracellular signals and the modulation of intracellular signal propagation, as well as cargo transport, the function most commonly attributed to this gene family.
Immunogen: Purified Lipoprotein Receptor-related Protein, Low Density. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing LRP1 are readily searchable from our website. Different antibodies against the same target such as LRP1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.