|The Lrp4 lrp4 (Catalog #MBS801705) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The LRP4 (Extracellular) Antibody: ATTO 390 reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s LRP4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC).
1ug/mL (WB). Researchers should empirically determine the suitability of the Lrp4 lrp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Lrp4 lrp4 product has the following accession number(s) (GI #224994223) (NCBI Accession #NP_766256.3) (Uniprot Accession #Q8VI56). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the LRP4 (Extracellular) Antibody: ATTO 390 with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Rat brain membrane lysate showing detection of LRP4 protein using Mouse Anti-LRP4 Monoclonal Antibody, Clone S207-27. Primary Antibody: Mouse Anti-LRP4 Monoclonal Antibody at 1:500, 1:1000, and 1:2000.)
Background Info: Detects ~215kDa. Degradation product can be seen at ~150kDa
Scientific Background: Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes. It is involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway.
Conjugate: ATTO 390. Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Lrp4 are readily searchable from our website. Different antibodies against the same target such as Lrp4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Abnormalities, Multiple, Atrophy, Brain Diseases, Disease Models, Animal, Hyperplasia, Inflammation, Kidney Diseases, Nervous System Diseases, Syndactyly, Tooth Abnormalities are some of the diseases may be linked to LRP4 (Extracellular) Antibody: ATTO 390. The following patways have been known to be associated with this gene. Bone, Brain, Embryonic Tissue, Eye tissues are correlated with this protein.