anti-M-CSF antibody product blog
Tags: Antibody; M-CSF; Monoclonal Antibody; anti-M-CSF antibody;
The M-CSF n/a (Catalog #MBS584294) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The M-CSF, Mouse, mAb ER-MP58 reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s M-CSF can be used in a range of immunoassay formats including, but not limited to, F, Flow Cytometry (FC/FACS).Application Use: For immunohistology and flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Researchers should empirically determine the suitability of the M-CSF n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The M-CSF n/a product has the following accession number(s) (GI #456957) (NCBI Accession #AAB29303.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Product Description: The monoclonal antibody ER-MP58 recognizes an antigen present on all mouse macrophage colony-stimulating factor (M-CSF) responsive cells in the bone marrow, including the earliest colony-forming myeloid progenitors, as well as by the majority of other myeloid precursors. The antigen is detected on a broad development range of macrophage precursor cells ut to the monocytic level, but also on grnaulocytes. ERxpression is rapidly lost upon maturation beyond the monocytic stage. The antigen disappears in the course of macrophage differentiation. Furthermore the antigen is clearly different from commenly used myeloid markers as Mac-1, F4/80, and Gr-1. The monoclonal antibody ER-MP58 is very useful for the identification of mouse myeloid hemopoietic islands in various organs, and for embryonal studies. Cells committed to the myeloid lineage can be separated from progenitor cells with other differentiation capacities by means of multiparameter cell sorting using monoclonal antibody ER-MP58 in combination with monoclonal antibody ER-MP12 (HM1084) and ER-MP-20 (HM1082).
In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing M-CSF are readily searchable from our website. Different antibodies against the same target such as M-CSF may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.