|The MAP4K4 map4k4 (Catalog #MBS831034) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MAP4K4 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s MAP4K4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).
WB: 1:500-1:2000. Researchers should empirically determine the suitability of the MAP4K4 map4k4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MAP4K4 map4k4 product has the following accession number(s) (GI #336020358) (NCBI Accession #NP_001229488.1) (Uniprot Accession #O95819). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the MAP4K4 antibody with the following immunoassay(s):
Western Blot (Western Blot analysis using MAP4K4 antibody
Western Blot showing MAP4K4 antibody used against truncated Trx-MAP4K4 recombinant protein (1), MBP-MAP4K4 (aa300-400) recombinant protein (2) and MAP4K4 (aa194-436)-hIgGFc transfected CH0-K1 cell lysate (3).)
Mouse monoclonal MAP4K4 antibody.
Biological Significance: MAP4K4 is the serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. MAP4K4 appears to act upstream of the JUN N-terminal pathway. Immunogen: MAP4K4 antibody was raised in Mouse using a purified recombinant fragment of MAP4K4(aa400-500) expressed in E Coli as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MAP4K4 are readily searchable from our website. Different antibodies against the same target such as MAP4K4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Brain, Heart, Liver, Lung, Lymph, Lymph Node, Muscle, Pancreas tissues are correlated with this protein. Adenocarcinoma, Brain Diseases, Cell Transformation, Neoplastic, Disease Models, Animal, Heart Diseases, Inflammation, Liver Diseases, Lung Diseases, Necrosis, Neoplasms, Experimental are some of the diseases may be linked to MAP4K4 antibody. MAP4K4 also interacts with the following gene(s): CHUK, IKBKB, MAP3K1, TRAF2. The following patways have been known to be associated with this gene.