anti-MCL1 antibody product blog
Tags: Antibody; MCL1; anti-MCL1 antibody; Monoclonal Antibody;
The MCL1 mcl1 (Catalog #MBS533538) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s MCL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB).ELISA: 1:10,000
IF: 1:200-1:1000
IHC: 1:200-1:1000
WB: 1:500-1:2000. Researchers should empirically determine the suitability of the MCL1 mcl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MCL1 mcl1 product has the following accession number(s) (GI #55959012) (NCBI Accession #CAI15504.1) (Uniprot Accession #Q07820). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the MCL1 antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot showing MCL1 antibody used against Hela (1), BCBL-1 (2), Jurkat (3) and HL60 (4) cell lysate.)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human lymphnode tissues using MCL1 antibody with DAB staining.)
Mouse monoclonal MCL1 antibody.
Biological Significance: MCL1 is a protein which belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing. Cross-Reactivity: Human
Immunogen: MCL1 antibody was raised in Mouse using a purified recombinant fragment of human MCL-1 expressed in E Coli as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MCL1 are readily searchable from our website. Different antibodies against the same target such as MCL1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Bone Marrow, Brain, Liver, Lung, Lymph Node, Prostate, Skin, Vascular tissues are correlated with this protein. Breast Neoplasms, Carcinoma, Hepatocellular, Inflammation, Liver Diseases, Liver Neoplasms, Lung Neoplasms, Multiple Myeloma, Necrosis, Neoplasms, Experimental, Pancreatic Neoplasms are some of the diseases may be linked to MCL1 antibody.