anti-MGL antibody product blog
Tags: Antibody; Monoclonal Antibody; MGL; anti-MGL antibody;
The MGL n/a (Catalog #MBS584265) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The MGL, Mouse, mAb ER-MP23 reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s MGL can be used in a range of immunoassay formats including, but not limited to, IHC-F, IHC-P, FC, FS.Application Use: For immunohistology and flow cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For blocking studies in vitro, dilutions have to be made according to the amounts of MGL to be inactivated. The antigen is glutaraldehyde (0.05%) resistant. Researchers should empirically determine the suitability of the MGL n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the MGL, Mouse, mAb ER-MP23 with the following immunoassay(s):
Immunohistochemistry (IHC-F: Immunohistochemistry on frozen C3H/HeN ear section stained with Clone ER-MP23 (5ug/ml))
Product Description: The monoclonal antibody ER-MP23 specifically reacts with the macrophage galactose-specific lectin (MGL), a 38 kDa single chain surface glycoprotein. MGL is found on murine mature macrophages in the connective tissue neighboring epithelia of e.g. salivary glands, capsule of lymph nodes, thymus and various other organs. MGL is present on the surface of connective tissue macrophages and their precursor cells in bone marrow. Also, MGL is expressed in macrophage cell lines (e.g. J774-1.6, RAW309Cr.1 and WR19M.1). Expression levels of MGL are increased in mature macrophages. The antigen is co expressed with the antigen recognized by monoclonal antibody BM8 (HM1066). The monoclonal antibody ER-MP23 has been raised after immunization of rats with mouse macrophage cell lines. Blocking studies demonstrated that the monoclonal antibody ER-MP23 is able to block mouse MGL.
Endotoxin: 2.95 EU/mg
Immunogen: Mouse macrophage cell lines
Aliases: Macrophage galactose-specific lectin, CD301, dendritic cell-asialoglycoprotein receptor, DC-ASGPR. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MGL are readily searchable from our website. Different antibodies against the same target such as MGL may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.