anti-MHC Class 1, H2, Kd, Dd antibody product blog
Tags: Antibody; Monoclonal Antibody; MHC Class 1, H2, Kd, Dd; anti-MHC Class 1, H2, Kd, Dd antibody;
The MHC Class 1, H2, Kd, Dd n/a (Catalog #MBS607019) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MHC Class 1, H2, Kd, Dd reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s MHC Class 1, H2, Kd, Dd can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Flow Cytometry (FC/FACS).Suitable for use in Flow Cytometry, Immunohistochemistry, Complement-mediated cytotoxicity.
Dilution: Flow Cytometry: 1ug/10e6 cells
Immunohistochemistry: acetone-fixed, frozen tissue sections. Researchers should empirically determine the suitability of the MHC Class 1, H2, Kd, Dd n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic alpha chains noncovalently associated with the invariant beta2-microglobulin.3,4 These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells.5 MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+ T cells during T cell ontogeny.3,6.
Immunogen: C3H.SW mouse splenocytes. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MHC Class 1, H2, Kd, Dd are readily searchable from our website. Different antibodies against the same target such as MHC Class 1, H2, Kd, Dd may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.