anti-MHC Class 2, I-Ak/s antibody product blog
Tags: Antibody; Monoclonal Antibody; MHC Class 2, I-Ak/s; anti-MHC Class 2, I-Ak/s antibody;
The MHC Class 2, I-Ak/s n/a (Catalog #MBS605607) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MHC Class 2, I-Ak/s (MHC Class II) reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s MHC Class 2, I-Ak/s can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS).Suitable for use in Flow Cytometry, Immunohistochemistry and Western Blot.
Dilution: Flow Cytometry: 1:50-1:100; 10ul labels 10e6 cells in 100ul
Immunohistochemistry (paraffin): 1:50-1:100
Immunohistochemistry: Frozen. Researchers should empirically determine the suitability of the MHC Class 2, I-Ak/s n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the H-2 region. In rats, this complex is referred to as the RT1 region. M3887-54B recognises a monomorphic determinant of the rat RT1B MHC class II antigen present on B lymphocytes, dendritic cells, some macrophages and certain epithelial cells. The literature reports that this clone does not react with the rat BDIX strain due to a defect in RT1B expression. M3887-54B also cross reacts with a polymorphic determinant on mouse strains of the H-2 haplotypes k and s. Analysis of recombinant mouse strains has mapped the OX-6 determinant to the H-2I-A region.
Immunogen: Rat thymocyte membrane glycoproteins. Hybridoma: NS1 myeloma cells with spleen cells from Balb/c mice. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MHC Class 2, I-Ak/s are readily searchable from our website. Different antibodies against the same target such as MHC Class 2, I-Ak/s may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.