anti-MICU1 antibody product blog
Tags: Antibody; Monoclonal Antibody; MICU1; anti-MICU1 antibody;
The MICU1 micu1 (Catalog #MBS2548891) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MICU1 Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s MICU1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF).WB: 1:500-1:2000
IHC: 1:100-1:200
IF: 1:100-1:300. Researchers should empirically determine the suitability of the MICU1 micu1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MICU1 micu1 product has the following accession number(s) (GI #306922382) (NCBI Accession #NP_001182447.1) (Uniprot Accession #Q9BPX6). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the MICU1 Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of 1) MCF7, 2) Mouse brain, 3) Rat brain with MICU1 Monoclonal Antibody.)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Mouse testis tissue using MICU1 Monoclonal Antibody at dilution of 1:200.)
Immunofluorescence (IF) (Immunofluorescence analysis of Human appendix tissue using MICU1 Monoclonal Antibody at dilution of 1:200.)
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.
Immunogen: Recombinant Protein
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.4
Conjugation: Unconjugated. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MICU1 are readily searchable from our website. Different antibodies against the same target such as MICU1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Brain, Heart, Liver, Lung, Muscle, Skin tissues are correlated with this protein.