anti-MLH1 antibody product blog
Tags: Antibody; Monoclonal Antibody; MLH1; anti-MLH1 antibody;
The MLH1 mlh1 (Catalog #MBS4156547) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-MLH1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s MLH1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemisty (IHC).Suggested Dilution: 1:1000-1:3000. Researchers should empirically determine the suitability of the MLH1 mlh1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MLH1 mlh1 product has the following accession number(s) (GI #4557757) (NCBI Accession #NP_000240.1) (Uniprot Accession #P40692). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-MLH1 Antibody with the following immunoassay(s):
Immunohistochemistry (IHC)
MutL Homolog 1 or MLH1, is a protein involved in the mismatch-repair pathway. Anti-MLH1 Antibody is ready to be used for detection of MLH1. This protein has been commonly associated with hereditary non-polyposis colorectal cancer thus is an useful marker for the disease. MLH1 is optimized when paired in an IHC panel with MSH6, MSH2, and PMS2.
Immunogen: Recombinant Human MLH1. Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MLH1 are readily searchable from our website. Different antibodies against the same target such as MLH1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Brain, Intestine, Liver, Lung, Lymph, Lymph Node, Ovary, Skin, Stomach tissues are correlated with this protein. Adenocarcinoma, Breast Neoplasms, Carcinoma, Colonic Neoplasms, Colorectal Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplasms, Neoplasms, Experimental, Ovarian Diseases, Ovarian Neoplasms are some of the diseases may be linked to Anti-MLH1 Antibody. MLH1 also interacts with the following gene(s): BLM, BRCA1, CASP3, EXO1, MBD4, MLH3, MSH4, MYC, PMS1, PMS2.