anti-Mouse TUG antibody product blog
Tags: Antibody; Monoclonal Antibody; Mouse TUG; anti-Mouse TUG antibody;
The Mouse TUG n/a (Catalog #MBS643933) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse TUG reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Mouse TUG can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Western Bloting: 1:500-1:2000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the Mouse TUG n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
The TUG protein contains an UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.
Immunogen: Purified recombinant fragment of TUG expressed in E. coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Mouse TUG are readily searchable from our website. Different antibodies against the same target such as Mouse TUG may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.