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anti-MX1 antibody product blog

Posted on 2015-11-09 19:53:27 by mybiosource_staff
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Tags: Antibody; Monoclonal Antibody; MX1; anti-MX1 antibody;
The MX1 mx1 (Catalog #MBS834739) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MX1 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s MX1 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Western Blot (WB).
IF: 1:100
WB: 1:2000. Researchers should empirically determine the suitability of the MX1 mx1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The MX1 mx1 product has the following accession number(s) (GI #222136617) (NCBI Accession #NP_002453) (Uniprot Accession #P20591). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the MX1 antibody with the following immunoassay(s):
Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant MX1 protein using MX1 antibody)
Immunofluorescence (IF) MX1.

Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant MX1 protein (Right) or empty vector (Left) detected with MX1 antibody)
Western Blot (WB) MX1.

Mouse monoclonal MX1 antibody.

Biological Significance: In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. MX1 is similar to the mouse protein as determined by its antigenic relatedness, induction conditions, physicochemical properties, and amino acid analysis. This cytoplasmic protein is a member of both the dynamin family and the family of large GTPases. In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. Immunogen: MX1 antibody was raised in mouse using a full length recombinant protein of human MX1 (NP_002453) produced in HEK293T cells, as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MX1 are readily searchable from our website. Different antibodies against the same target such as MX1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adenocarcinoma, Breast Neoplasms, Cardiovascular Diseases, Inflammation, Influenza in Birds, Influenza, Human, Lung Diseases, Necrosis, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to MX1 antibody. Blood, Bone, Brain, Heart, Kidney, Liver, Lung, Skin, Spleen, Vascular tissues are correlated with this protein.
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