anti-N-Ethylmaleimide-sensitive fusion protein antibody product blog
Tags: Antibody; Monoclonal Antibody; NSF; anti-N-Ethylmaleimide-sensitive fusion protein antibody; N-Ethylmaleimide-sensitive fusion protein;
The NSF nsf (Catalog #MBS565054) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The NSF monoclonal antibody (9G7-3) reacts with Human, Mouse, Rat, Bovine, Chicken, Dog, Hamster, Monkey, Porcine, Rabbit, Sheep and may cross-react with other species as described in the data sheet. MyBioSource\'s NSF can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) (PS), Western Blot (WB).Western Blot (1:1,000, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Detects a band of ~76kDa by Western blot. Researchers should empirically determine the suitability of the NSF nsf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NSF nsf product has the following accession number(s) (GI #257051048) (NCBI Accession #P46459.3) (Uniprot Accession #P46459). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NSF monoclonal antibody (9G7-3) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis: Lane 1: MW marker, Lane 2: HeLa (Heat Shocked), Lane 3: Vero, Lane 4: CHO-K1, Lane 5: ESK-4.)
N-ethylmaleimide-sensitive factor (NSF) is involved in a variety of membrane fusion events and plays a prominent role in synaptic vesicle fusion. In order to interact with target membranes, NSF requires another set of soluble proteins called Soluble NSF attachment proteins (SNAPs). Together with synaptotagmin and alpha-SNAP, NSF modulates the interaction of SNAP25, VAMP, and syntaxin in an ATP-dependent manner to form a 20S complex involved in synaptic vesicle docking and fusion.
Immunogen: Recombinant bovine NSF. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NSF are readily searchable from our website. Different antibodies against the same target such as NSF may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. NSF also interacts with the following gene(s): GABARAP, GOSR1, NAPA, STX4, VAMP2, VAMP7, YKT6. The following patways have been known to be associated with this gene. Brain Diseases, Brain Injuries, Disease Models, Animal, Fibrosis, Hypertension, Inflammation, Kidney Diseases, Mental Disorders, Nervous System Diseases, Seizures are some of the diseases may be linked to NSF monoclonal antibody (9G7-3).