anti-NALCN antibody product blog
Tags: Antibody; Monoclonal Antibody; NALCN; anti-Nalcn antibody;
The NALCN nalcn (Catalog #MBS190655) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s NALCN can be used in a range of immunoassay formats including, but not limited to, Immunoblot (IB).Immunoblotting: Use at 1ug/ml. Researchers should empirically determine the suitability of the NALCN nalcn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NALCN nalcn product has the following accession number(s) (GI #39992643) (NCBI Accession #AAH64343.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NALCN Monoclonal Antibody with the following immunoassay(s):
Testing Data
NALCN (sodium leak channel non-selective protein) is a 1,738 amino acid multi-pass membrane protein in the cation-nonselective channel family. NALCN is highly conserved in mammalian species and is widely expressed in the central nervous system. NALCN is a voltage-independent, non-selective cation channel which is permeable to sodium, potassium, and calcium ions. It is responsible for background sodium ion leak conductance in neurons and regulates basal excitability of the nervous system. Three isoforms of NALCN result from alternative splicing events.
Antigen: Fusion protein corresponding to aa 1659-1738 (cytoplasmic C-terminus) of rat NALCN (accession no.Q6Q760). Positive Control: Rat brain lysate.
Dilution Instructions: Dilute in PBS or medium which is identical to that used in the assay system. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NALCN are readily searchable from our website. Different antibodies against the same target such as NALCN may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Brain, Embryonic Tissue, Intestine, Lung, Muscle, Pancreas, Uncharacterized Tissue tissues are correlated with this protein. Atrophy, Disease Models, Animal, Growth Disorders, Neurobehavioral Manifestations are some of the diseases may be linked to NALCN Monoclonal Antibody.