anti-NEFL antibody product blog
Tags: Antibody; Monoclonal Antibody; NEFL; anti-NEFL antibody;
The NEFL nefl (Catalog #MBS476249) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-NEFL Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s NEFL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the NEFL nefl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The NEFL nefl product has the following accession number(s) (GI #105990539) (NCBI Accession #NP_006149.2) (Uniprot Accession #P07196). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-NEFL Mouse mAb with the following immunoassay(s):
Western Blot (WB) (Western blot analysis using NEFL mAb against human NEFL (AA)
Western Blot (WB) (Western blot analysis using NEFL mouse mAb against Hela (1) and Jurkat (2) cell lysate.)
Immunofluorescence (IF) (Immunofluorescence analysis of Hela cells using NEFL mouse mAb (green). Blue)
Flow Cytometry (FC/FACS) (Flow cytometric analysis of Jurkat cells using NEFL mouse mAb (green) and negative control (red).)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded lung cancer tissues using NEFL mouse mAb with DAB staining.)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using NEFL mouse mAb with DAB staining.)
Entrez Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
Immunogen: Purified recombinant fragment of human NEFL expressed in E Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NEFL are readily searchable from our website. Different antibodies against the same target such as NEFL may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.