anti-NESP55,GNAS antibody product blog
Tags: Antibody; Monoclonal Antibody; NESP55,GNAS; anti-NESP55,GNAS antibody;
The GNAS gnas (Catalog #MBS2540265) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The GNAS Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s GNAS can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA).WB: 1:1000-1:10000
IHC: 1:50-1:500. Researchers should empirically determine the suitability of the GNAS gnas for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GNAS gnas product has the following accession number(s) (GI #4504047) (NCBI Accession #NP_000507.1) (Uniprot Accession #O95467). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GNAS Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of fetal Human brain tissue using NESP55/GNAS Monoclonal Antibody at dilution of 1:2000)
Guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 (GNAS1) is the ubiquitously expressed heterotrimeric G protein that couples receptors to the effector enzyme adenylyl cyclase and is required for receptor-stimulated intracellular cAMP generation. Mutations of Gs(alpha) residues involved in the GTPase reaction that lead to constitutive activation are present in endocrine tumors, fibrous dysplasia of bone, and McCune-Albright syndrome. The molecular weight of Gs(alpha) protein is about 46 kDa.
Immunogen: Fusion protein of NESP55/GNAS. Buffer: PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation: Unconjugated. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GNAS are readily searchable from our website. Different antibodies against the same target such as GNAS may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Kidney, Muscle, Nerve, Pancreas, Parathyroid, Skin, Thyroid tissues are correlated with this protein. GNAS also interacts with the following gene(s): ADCY5, ADRB2, GHRHR, GNB1, LHCGR, TSHR. Albright\'s hereditary osteodystrophy, Endocrine System Diseases, Fibrous Dysplasia, Polyostotic, Kidney Diseases, Obesity, Ossification, Heterotopic, PSEUDOHYPOPARATHYROIDISM, TYPE IA, Pseudohypoparathyroidism, Pseudohypoparathyroidism Type 1B, Pseudopseudohypoparathyroidism are some of the diseases may be linked to GNAS Monoclonal Antibody.