anti-Neu antibody product blog
Tags: Antibody; Monoclonal Antibody; Neu; anti-Neu antibody;
The Neu n/a (Catalog #MBS530119) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Neu antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Neu can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB).IHC: 1:200-1:400
IP: 2 ug/mg protein lysate
WB: 1-2 ug/ml. Researchers should empirically determine the suitability of the Neu n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Neu antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Formalin-fixed, paraffin-embedded human breast carcinoma stained with Neu antibody using peroxidase-conjugate and AEC chromogen. Note intense cell membrane staining of tumor cells.)
Mouse monoclonal Neu antibody.
Biological Significance: c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein. Cross-Reactivity: Human, mouse, rat
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
Immunogen: Neu antibody was raised in mouse using cytoplasmic domain of recombinant human c-erbB-2/HER-2 as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Neu are readily searchable from our website. Different antibodies against the same target such as Neu may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.