|The Neurofilament H, 200kD n/a (Catalog #MBS632209) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Neurofilament H, 200kD (NF-H) reacts with Chicken, Human, Mouse, Porcine, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Neurofilament H, 200kD can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).
Suitable for use in Immunohistochemistry and Western Blot.
Dilution: Western Blot: MAP1B and Tau
Immunohistochemistry (Frozen, Paraffin): 1:50-1:100
Note: Does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Researchers should empirically determine the suitability of the Neurofilament H, 200kD n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
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Neurofilaments can be defined as the intermediate or 10nm filaments found in specifically in neuronal cells. In the electron microscope neurofilaments appear as 10nm diameter fibres of indeterminate length which generally have fine wispy protrusions from their sides. They are found particularly abundantly in axons of large projection neurons. They probably function to provide structural support for neurons and their synapses and to support the large axon diameters required for rapid conduction of impulses down axons. They are composed a mixture of subunits which usually include the three neurofilament triplet proteins known as NFL, NFM and NFH. Neurofilaments may also include smaller amounts of peripherin, alpha internexin, nestin and in some cases vimentin. Antibodies to the various neurofilament subunits are very useful cell type markers since the proteins are among the most abundant of the nervous system, are expressed only in neurons and are biochemically very stable.
Immunogen: Neurofilament H, 200kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Neurofilament H, 200kD are readily searchable from our website. Different antibodies against the same target such as Neurofilament H, 200kD may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.