anti-NF-L antibody product blog
Tags: Antibody; Monoclonal Antibody; NF-L; anti-NF-L antibody;
The NF-L nefl (Catalog #MBS2541999) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Neurofilament Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Neurofilament can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA).WB: 1:500-1:5000
IHC: 1:20-1:200. Researchers should empirically determine the suitability of the NF-L nefl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NF-L nefl product has the following accession number(s) (GI #105990539) (NCBI Accession #NP_006149.2) (Uniprot Accession #P07196). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Neurofilament Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Human stomach tissue using NF-L Monoclonal Antibody at dilution of 1:1000)
NEFL, also named as NF68 and NFL, belongs to the intermediate filament family. Neurofilaments are the 10nm intermediate filaments found specifically in neurons. They are a major component of the cell\'s cytoskeleton, and provide support for normal axonal radial growth. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The names given to the three major neurofilament subunits are based upon the apparent molecular weight of the mammalian subunits on SDS-PAGE:NF-L, 65-68kd; NF-M, 145-160kd and NF-H, 200-220kd. This antibody is specific to NEFL. It has a very weak reaction to NEFM.
Immunogen: Fusion protein of NF-L. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NF-L are readily searchable from our website. Different antibodies against the same target such as NF-L may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bone Marrow, Brain, Embryonic Tissue, Eye, Ganglia, Kidney, Lung, Nerve, Prostate, Spinal Cord tissues are correlated with this protein. The following patways have been known to be associated with this gene. NF-L also interacts with the following gene(s): GAN, MTMR2, NEFH, NEFM, TSC1. Ataxia, Brain Diseases, Breast Neoplasms, Charcot-Marie-Tooth disease, Type 1F, Disease Models, Animal, Hypertension, Lung Neoplasms, Nervous System Diseases, Nervous System Malformations, Pain are some of the diseases may be linked to Neurofilament Monoclonal Antibody.