Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Monoclonal Antibody Blog  rightarrow anti-NF1P5 antibody  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
separator
 • anti-HSPH1 antibody blog
 • anti-CA 125 antibody blog
 • AR antibody blog
 • anti-H3 antibody blog
 • anti-BMP2 antibody blog
 • UACA antibody blog
 • anti-MSH6 antibody blog
 • anti-DNAL4 antibody blog
 • anti-PTH antibody blog
 • anti-MMP9 antibody blog
 • anti-SPP1 antibody blog
 • anti-SMYD1 antibody blog
 • anti-Ahsa1 antibody blog
 • anti-AKT3 antibody blog
 • anti-Hsp70/Hsc70 antibody blog
 • anti-HPTII antibody blog
 • anti-HNF1B antibody blog
 • anti-APC-AAT antibody blog
 • anti-PTH antibody blog
 • anti-MCP1 antibody blog
separator
Blog Categories separator
separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
separator
Our Best Sellers moreseparator
separator
 • Quinolinic Acid (QA) ELISA Kit
 • A Disintegrin And Metalloproteinase With Thrombospondin 1 (A... Antibody
 • CytoSelect 48-well Cell Adhesion Assay (Collagen IV, Colorim... Assay Kit
 • SIRT2 Antibody
 • CDKN2C Antibody
 • Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Antibody
 • E Selectin Antibody
 • C-EBP-alpha Antibody
 • Complement fragment 3a (C3a) ELISA Kit
 • Cystatin-C (CST3) Native Protein
 • Cerebellin 1 (CBLN1) ELISA Kit
 • Osteonectin (SPARC) Native Protein
 • Colon Lysate
 • E-Selectin Western Blot Control
 downarrow more ...
separator

anti-NF1P5 antibody product blog

separator
Posted on 2015-11-23 08:45:56 by mybiosource_staff
Share it on ...     
separator
separator
Tags: Antibody; Monoclonal Antibody; HSP90 ; anti-NF1P5 antibody; NF1P5;
separator
The NF1P5 n/a (Catalog #MBS803038) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Hsp90 Antibody: APC reacts with Human, Rabbit, Rat, Mouse, Chicken, Achyla, Wheat Germ, Sf9 cell line and may cross-react with other species as described in the data sheet. MyBioSource\'s Hsp90 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).
1 ug/ml was sufficient for detection of hsp90 by Western Blot in 20 ug of HeLa lysate. Researchers should empirically determine the suitability of the NF1P5 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The NF1P5 n/a product has the following accession number(s) (GI #22086553) (NCBI Accession #AAM90675.1) (Uniprot Accession #Q8LLI5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Hsp90 Antibody: APC with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry analysis using Mouse Anti-Hsp90 Monoclonal Antibody, Clone AC-16. Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 Monoclonal Antibody at 1:2000 for 12 hours at 4 degree C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 ul for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Inflammatory cells.)
Immunohistochemistry (IHC) NF1P5.

Immunohistochemistry (IHC) (Immunohistochemistry analysis using Mouse Anti-Hsp90 Monoclonal Antibody, Clone AC-16. Tissue: inflamed colon. Species: Mouse. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 Monoclonal Antibody at 1:2000 for 12 hours at 4 degree C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 ul for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Mostly inflammatory cells, some mucosa.)
Immunohistochemistry (IHC) NF1P5.

Background Info: This antibody is reactive with both the constitutive and the inducible form of Hsp90. It does not bind to the native form and does not recognize Hsp90 from E.coli or yeast.

Scientific Background: Hsp90 is a highly conserved and essential stress protein that is expressed in all eukaryotic cells. From a functional perspective, hsp90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of a chaperone complex (1-4). Despite its label of being a heat-shock protein, hsp90 is one of the most highly expressed proteins in unstressed cells (1-2% of cytosolic protein). It carries out a number of housekeeping functions - including controlling the activity, turnover, and trafficking of a variety of proteins. Most of the hsp90-regulated proteins that have been discovered to date are involved in cell signaling (5-6). The number of proteins now know to interact with Hsp90 is about 100. Target proteins include the kinases v-Src, Wee1, and c-Raf, transcriptional regulators such as p53 and steroid receptors, and the polymerases of the hepatitis B virus and telomerase.5 When bound to ATP, Hsp90 interacts with co-chaperones Cdc37, p23, and an assortment of immunophilin-like proteins, forming a complex that stabilizes and protects target proteins from proteasomal degradation. In most cases, hsp90-interacting proteins have been shown to co-precipitate with hsp90 when carrying out immuno-adsorption studies, and to exist in cytosolic heterocomplexes with it. In a number of cases, variations in hsp90 expression or hsp90 mutation has been shown to degrade signaling function via the protein or to impair a specific function of the protein (such as steroid binding, kinase activity) in vivo. Ansamycin antibiotics, such as geldanamycin and radicicol, inhibit hsp90 function (7).

horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions