|The NHEJ1 nhej1 (Catalog #MBS832323) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The NHEJ1 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s NHEJ1 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB).
WB: 1:500-2000. Researchers should empirically determine the suitability of the NHEJ1 nhej1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NHEJ1 nhej1 product has the following accession number(s) (GI #13376142) (NCBI Accession #NP_079058) (Uniprot Accession #Q9H9Q4). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NHEJ1 antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant NHEJ1 protein (Right) or empty vector (Left) detected with NHEJ1 antibody)
Immunohistochemistry (IHC) (Immunohistochemical analysis of NHEJ1 protein in paraffin embedded Human liver tissue using NHEJ1 antibody)
Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant NHEJ1 protein using NHEJ1 antibody)
Mouse monoclonal NHEJ1 antibody.
Biological Significance: Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the non homologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Immunogen: NHEJ1 antibody was raised in mouse using a full length recombinant protein of human NHEJ1 (NP_079058) produced in HEK293T cells, as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NHEJ1 are readily searchable from our website. Different antibodies against the same target such as NHEJ1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. NHEJ1 also interacts with the following gene(s): DCLRE1C, LIG4, PRKDC, XRCC4, XRCC5. Blood, Bone Marrow, Brain, Eye, Liver, Lung, Prostate tissues are correlated with this protein. Adenocarcinoma, Carcinoma, Hepatocellular, Cell Transformation, Neoplastic, Congenital Abnormalities, Eye Abnormalities, Inflammation, Learning Disorders, Liver Diseases, Nervous System Diseases, Nervous System Malformations are some of the diseases may be linked to NHEJ1 antibody.