anti-Nlgn4l antibody product blog
Tags: Antibody; Monoclonal Antibody; Neuroligin 4; anti-Nlgn4l antibody; Nlgn4l;
The Nlgn4l nlgn4l (Catalog #MBS801335) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Neuroligin 4 Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Neuroligin 4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), IF-p.1:1000 WB. Researchers should empirically determine the suitability of the Nlgn4l nlgn4l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Nlgn4l nlgn4l product has the following accession number(s) (GI #152002336) (NCBI Accession #ABS19580) (Uniprot Accession #B0F2B4). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Neuroligin 4 Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry analysis using Mouse Anti-Neuroligin 4 Monoclonal Antibody, Clone S98-7. Tissue: Dentate Gyrus. Species: Mouse. Fixation: formaldehyde-fixed paraffin embedded. Primary Antibody: Mouse Anti-Neuroligin 4 Monoclonal Antibody at 1:100. Secondary Antibody: FITC Goat Anti-Mouse (green). Counterstain: DAPI (blue) nuclear stain at 1:1000. Courtesy of: Rachel Reith, NIH/NIMH.)
Background Info: Detects a 125-130 kDa protein.
Scientific Background: This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large (Drosophila) homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene.
Certificate of Analysis: 1ug/mL was sufficient for detection of Neuroligin 4 in 20 ug of mouse brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Storage Buffer: PBS pH 7.4, 50% glycerol, 0.1% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Nlgn4l are readily searchable from our website. Different antibodies against the same target such as Nlgn4l may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.