|The NNMT nnmt (Catalog #MBS833923) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The NNMT antibody reacts with Human, Dog and may cross-react with other species as described in the data sheet. MyBioSource\'s NNMT can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB).
WB: 1:500-2000. Researchers should empirically determine the suitability of the NNMT nnmt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NNMT nnmt product has the following accession number(s) (GI #5453790) (NCBI Accession #NP_006160) (Uniprot Accession #P40261). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NNMT antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant NNMT protein (Right) or empty vector (Left) detected with NNMT antibody)
Immunohistochemistry (IHC) (Immunohistochemical analysis of NNMT protein in paraffin embedded Human prostate tissue using NNMT antibody)
Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant NNMT protein using NNMT antibody)
Mouse monoclonal NNMT antibody.
Biological Significance: N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. NNMT responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor. N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. Immunogen: NNMT antibody was raised in mouse using a full length recombinant protein of human NNMT (NP_006160) produced in HEK293T cells, as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NNMT are readily searchable from our website. Different antibodies against the same target such as NNMT may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. NNMT also interacts with the following gene(s): AHCY, AOX1, IL6, MMP2, STAT3. Adipose Tissue, Ascites, Brain, Heart, Kidney, Liver, Lung, Mouth, Pancreas, Uterus tissues are correlated with this protein. The following patways have been known to be associated with this gene. Adenocarcinoma, Breast Neoplasms, Fatty Liver, Inflammation, Kidney Diseases, Liver Diseases, Liver Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Experimental are some of the diseases may be linked to NNMT antibody.