anti-NUCB1 antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-NUCB1 antibody; NUCB1;
The NUCB1 n/a (Catalog #MBS838484) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s NUCB1 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Western Blot (WB).IF: 1:100
WB: 1:500. Researchers should empirically determine the suitability of the NUCB1 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NUCB1 antibody with the following immunoassay(s):
Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant NUCB1 protein using NUCB1 antibody)
Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant NUCB1 protein (Right) or empty vector (Left) detected with NUCB1 antibody)
Mouse monoclonal NUCB1 antibody.
Biological Significance: Calnuc or NUCB1 belongs to the nucleobindin family. It is a major calcium-binding protein of the Golgi and is a good Golgi marker. It may be involved in calcium homeostasis. Calnuc also plays roles in regulation of levels of amyloid precursor protein (APP) and its proteolytic metabolites to further affect the patho/physiological functions of APP including Alzheimer\'s disease pathogenesis. Cross-Reactivity: Human
Immunogen: NUCB1 antibody was raised in mouse using a full length recombinant protein of human NUCB1 (NP_006175) produced in HEK293T cells, as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NUCB1 are readily searchable from our website. Different antibodies against the same target such as NUCB1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.