|The NUP133 nup133 (Catalog #MBS6002708) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The NUP133 (Nuclear Pore Complex Protein Nup133, Nucleoporin Nup133, Nucleoporin 133kDa, 133kD Nucleoporin, hNUP133, FLJ10814, MGC21133) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s NUP133 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC).
Suitable for use in ELISA, Immunohistochemistry and Western Blot.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 3ug/ml. Researchers should empirically determine the suitability of the NUP133 nup133 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NUP133 nup133 product has the following accession number(s) (GI #486563) (NCBI Accession #CAA82161.1) (Uniprot Accession #P36161). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
LKLEILCKAL QRDNWSSSDG KDDPIEVSKD SIFVKILQKL LKDGIQLSEY LPEVKDLLQA DQLGSLKSNP YFEFVLKANY EYYVQGQ.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. The nucleoporin protein displays evolutionarily conserved interactions with other nucleoporins. This protein, which localizes to both sides of the nuclear pore complex at interphase, remains associated with the complex during mitosis and is targeted at early stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells.
Immunogen: Partial recombinant corresponding to aa1069-1156 from human NUP133 (NP_060700) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NUP133 are readily searchable from our website. Different antibodies against the same target such as NUP133 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. NUP133 also interacts with the following gene(s): NUP120, NUP145, NUP49, NUP84, NUP85, SEC13, SEH1.