|The OPHN1 ophn1 (Catalog #MBS2542008) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Oligophrenin 1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Oligophrenin 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).
WB: 1:200-1:2000. Researchers should empirically determine the suitability of the OPHN1 ophn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The OPHN1 ophn1 product has the following accession number(s) (GI #3059135) (Uniprot Accession #O60890). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
The OPHN1 gene encodes a Rho-GTPase activating protein (RhoGAP), and mutations in OPHN1 are responsible for non-specific X-linked mental retardation (NSMR). OPHN1 is highly expressed in the brain and present both pre- and postsynaptically in neurons.
Immunogen: Oligophrenin 1 fusion protein ag1224
Buffer: PBS with 0.1% sodium azide and 50% glycerol pH 7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing OPHN1 are readily searchable from our website. Different antibodies against the same target such as OPHN1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. OPHN1 also interacts with the following gene(s): ARHGEF6, CDC42, FGD1, MCF2, RHOA. Brain, Embryonic Tissue, Eye, Kidney, Muscle, Prostate, Skin, Testis, Uterus, Vascular tissues are correlated with this protein. Atrophy, Cardiovascular Diseases, Disease Models, Animal, Hypertrophy, Learning Disorders, Memory Disorders, Mental Retardation, X-Linked, Nervous System Diseases, Neurobehavioral Manifestations, Vascular Diseases are some of the diseases may be linked to Oligophrenin 1 Antibody. The following patways have been known to be associated with this gene.