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anti-ORAI1 antibody product blog

Posted on 2017-03-03 19:58:23 by mybiosource_staff
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Tags: Antibody; Monoclonal Antibody; ORAI1; anti-ORAI1 antibody;
The ORAI1 orai1 (Catalog #MBS2542010) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ORAI1 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ORAI1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA).
WB: 1:500-1:5000
IHC: 1:50-1:500. Researchers should empirically determine the suitability of the ORAI1 orai1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The ORAI1 orai1 product has the following accession number(s) (GI #38016943) (NCBI Accession #NP_116179.2) (Uniprot Accession #Q96D31). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ORAI1 Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of HL-60 cells using ORAI1 Monoclonal Antibody at dilution of 1:1000)
Western Blot (WB) ORAI1.

Store-operated calcium channels (SOCs) play essential functions in various physiological processes. Orai1 (also named CRACM1) is a critical molecular component of SOCs. Orai1 protein is a 32-55 kDa plasma membrane protein with 4 transmembrane domains. Human patients with a severe combinaed immunodeficiency (SCID) syndrome possess point mutations in Orai1 gene.

Immunogen: Fusion protein of ORAI1. Buffer: PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation: Unconjugated. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ORAI1 are readily searchable from our website. Different antibodies against the same target such as ORAI1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. ORAI1 also interacts with the following gene(s): CCND1, ITPR3, STIM1, STIM2, TRPC1, TRPC3, TRPC6. Blood, Bone, Bone Marrow, Brain, Embryonic Tissue, Heart, Kidney, Lung, Salivary Gland, Skin tissues are correlated with this protein. The following patways have been known to be associated with this gene. Breast Neoplasms, Cardiovascular Diseases, Disease Models, Animal, Hyperplasia, Hypertension, Hypertrophy, Inflammation, Kidney Diseases, Necrosis, Nervous System Diseases are some of the diseases may be linked to ORAI1 Monoclonal Antibody.
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