|The p53 tp53 (Catalog #MBS533109) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The p53 antibody reacts with To be determined by the end user and may cross-react with other species as described in the data sheet. MyBioSource\'s p53 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the p53 tp53 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The p53 tp53 product has the following accession number(s) (GI #23491729) (NCBI Accession #BAC16799.1) (Uniprot Accession #P04637). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Mouse monoclonal p53 Protein antibody.
Biological Significance: p53 becomes activated in response to a myriad of stress types, which include but are not limited to DNA damage (induced by either UV, IR, or chemical agents such as hydrogen peroxide), oxidative stress, osmotic shock, ribonucleotide depletion, and deregulated oncogene expression. Immunogen: p53 antibody was raised in mouse using recombinant human p53 (transcription domain within the NH2 terminus) as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing p53 are readily searchable from our website. Different antibodies against the same target such as p53 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bladder, Blood, Bone, Brain, Liver, Lung, Lymph, Lymph Node, Prostate, Skin tissues are correlated with this protein. Breast Neoplasms, Carcinoma, Carcinoma, Small Cell, Carcinoma, Squamous Cell, Cell Transformation, Neoplastic, Colorectal Neoplasms, Glioma, Liver Neoplasms, Neoplasm Metastasis, Sarcoma are some of the diseases may be linked to p53 antibody. The following patways have been known to be associated with this gene.