anti-PAI1 antibody product blog
Tags: Antibody; Monoclonal Antibody; PAI1; anti-PAI1 antibody;
The PAI1 serpine1 (Catalog #MBS838119) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PAI1 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s PAI1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), AP. Researchers should empirically determine the suitability of the PAI1 serpine1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The PAI1 serpine1 product has the following accession number(s) (GI #27806497) (NCBI Accession #NP_776562.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Mouse monoclonal PAI1 antibody.
Biological Significance: PAI1 is a serine protease inhibitor (serpin) that functions as the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), the activators of plasminogen and hence fibrinolysis (the physiological breakdown of blood clots). Cross-Reactivity: Human
Immunogen: PAI1 antibody was raised in Mouse using Partiallty purified human PAI1 as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PAI1 are readily searchable from our website. Different antibodies against the same target such as PAI1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Atherosclerosis, Cardiovascular Diseases, Disease Models, Animal, Fibrosis, Heart Diseases, Hypertension, Inflammation, Necrosis, Obesity, Thrombosis are some of the diseases may be linked to PAI1 antibody. PAI1 also interacts with the following gene(s): PLAT, PLAU, PLAUR, PLG, SMAD2, SMAD4, TGFB1, TIMP1, VTN. Adipose Tissue, Blood, Extraembryonic Tissue, Intestine, Kidney, Lung, Mammary Gland, Muscle, Reticulum, Uncharacterized Tissue tissues are correlated with this protein.