anti-PAICS antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-PAICS antibody; PAICS;
The PAICS paics (Catalog #MBS832682) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s PAICS can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB).FC: 1:100
IF: 1:100
WB: 1:500-2000. Researchers should empirically determine the suitability of the PAICS paics for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PAICS paics product has the following accession number(s) (GI #5453539) (NCBI Accession #NP_006443) (Uniprot Accession #P22234). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PAICS antibody with the following immunoassay(s):
Flow Cytometry (FC/FACS) (Flow Cytometric analysis of HEK293T cells transfected with either recombinant PAICS protein (red) or empty vector (blue) stained using PAICS antibody)
Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant PAICS protein (Right) or empty vector (Left) detected with PAICS antibody)
Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant PAICS protein using PAICS antibody)
Mouse monoclonal PAICS antibody.
Biological Significance: PAICS is a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. Cross-Reactivity: Human
Immunogen: PAICS antibody was raised in mouse using a full length recombinant protein of human PAICS (NP_006443) produced in HEK293T cells, as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PAICS are readily searchable from our website. Different antibodies against the same target such as PAICS may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Cell Transformation, Neoplastic, Lung Diseases, Lung Neoplasms, Neoplasm Metastasis are some of the diseases may be linked to PAICS antibody. Blood, Brain, Eye, Lung, Muscle, Ovary, Prostate, Skin tissues are correlated with this protein. PAICS also interacts with the following gene(s): ADSL, ATIC, GART, PFAS, PPAT.