anti-PAR / Poly ADP-Ribose antibody product blog
Tags: Antibody; Monoclonal Antibody; PAR / Poly ADP-Ribose; anti-PAR / Poly ADP-Ribose antibody;
The PAR / Poly ADP-Ribose n/a (Catalog #MBS249333) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-PAR / Poly ADP-Ribose Antibody (clone 10H) IHC-plus reacts with Drosophila, Rat, Mouse, Human and may cross-react with other species as described in the data sheet. MyBioSource\'s PAR / Poly ADP-Ribose can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC), Western Blot (WB), Flow Cytometry (FC/FACS).ICC (5 - 20 ug/ml)
IHC-P (10 ug/ml)
WB (5 ug/ml). Researchers should empirically determine the suitability of the PAR / Poly ADP-Ribose n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-PAR / Poly ADP-Ribose Antibody (clone 10H) IHC-plus with the following immunoassay(s):
Immunohistochemistry - Paraffin (IHC) (Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))
Poly (ADP-ribose) is synthesized by poly(ADP-ribose) polymerases (PARP), which catalyzes the formation of the polymer PADPR, with chain lengths ranging from 2 to 300 residues. PARP is found in the cell\'s nucleus. The main role is to detect and signal single-strand DNA breaks (SSB) to the enzymatic machinery involved in the SSB repair. PARP activation is an immediate cellular response to metabolic, chemical, or radiation-induced DNA SSB damage.
Immunogen: Purified poly(ADP-ribose).
Immunogen Description: Purified poly(ADP-ribose).
Immunogen Type: Purified protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PAR / Poly ADP-Ribose are readily searchable from our website. Different antibodies against the same target such as PAR / Poly ADP-Ribose may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.