Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource  rightarrow Monoclonal Antibody Blog  rightarrow anti-PARP antibody  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
 • anti-Snca antibody blog
 • anti-MSi-1 antibody blog
 • anti-CD3 antibody blog
 • anti-IFN gamma antibody blog
 • anti-RhoD human antigen IgG1 antibody blog
 • anti-CD10 antibody blog
 • anti-DUX4L1 antibody blog
 • anti-HOXA9 antibody blog
 • anti-RT1.Bu antibody blog
 • anti-Galectin3 / Mac2 antibody blog
 • anti-MET antibody blog
 • anti-HPV antibody blog
 • anti-CD150 antibody blog
 • anti-CD74 antibody blog
 • anti-IL1RAPL1 antibody blog
 • anti-EphB4  antibody blog
 • anti-LM ActA antibody blog
 • anti-MCL1 antibody blog
 • anti-SATB1 antibody blog
 • anti-GABA-A antibody blog
Blog Categories separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
Our Best Sellers moreseparator
 • NERVE GROWTH FACTOR 2.5S (Ngf) Purified Protein
 • Hantavirus, Glycoprotein N Antibody
 • Total Leukotriene (LT) ELISA Kit
 • Laminin subunit gamma-2 (LAMC2) ELISA Kit
 • Canine Immunoglobulin Antibody
 • PIPOX Antibody
 • PRMT7 Antibody
 • Cytomegalovirus pP28 (UL99) (CMV pp28) Recombinant Protein
 • Tumor Necrosis Factor Alpha (TNFa) ELISA Kit
 • Prolipoprotein diacylglyceryl transferase (lgt) Recombinant Protein
 • Anti-IgA Antibody ELISA Kit
 • Insulin-degrading enzyme (Ide) ELISA Kit
 • ZKSCAN3 cDNA Clone
 downarrow more ...

anti-PARP antibody product blog

Posted on 2016-01-07 09:00:56 by mybiosource_staff
Share it on ...     
Tags: Antibody; PARP; Monoclonal Antibody; anti-PARP antibody;
The PARP parp1 (Catalog #MBS840142) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PARP Antibody (Clone 10H) reacts with All species and may cross-react with other species as described in the data sheet. MyBioSource\'s PARP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA), Immunocytochemistry (ICC), Immunohistochemistry (IHC).
Immunocytochemistry : 5-20 mug/ml; Western Blot (10 mug/ml using colorimetric methods; <2 mug/ml for ECL); Immunoprecipitation and ELISA. Researchers should empirically determine the suitability of the PARP parp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The PARP parp1 product has the following accession number(s) (GI #156523968) (NCBI Accession #NP_001609). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PARP Antibody (Clone 10H) with the following immunoassay(s):
Testing Data
Testing Data PARP.

Background: PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, is a highly conserved nuclear enzyme implicated in DNA repair and in the apoptosis response of cells. This protein can be cleaved by many caspases in vitro and is one of the main cleavage targets of caspase-3 in vivo. The cleavage occurs between ASP214 and Gly 215, which separates PARP\'s N-terminal DNA binding domain (24 kDa) from its C-terminal catalytic domain (89 kDa). It has been shown that cleavage of PARP facilitates cellular disassembly and inhibition of PARP cleavage attenuates apoptosis in vitro.

Positive Control: Tested by ICC in rat liver tissues. Handling: The antibody solution should be gently mixed before use. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PARP are readily searchable from our website. Different antibodies against the same target such as PARP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. PARP also interacts with the following gene(s): CASP3, CASP7, PARG, PCNA, TP53, UBC, WRN, XRCC1, XRCC5, XRCC6. Blood, Brain, Heart, Kidney, Liver, Lung, Muscle, Nerve, Prostate, Vascular tissues are correlated with this protein. Brain Ischemia, Breast Neoplasms, Heart Diseases, Inflammation, Liver Diseases, Liver Neoplasms, Lung Neoplasms, Necrosis, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to PARP Antibody (Clone 10H). The following patways have been known to be associated with this gene.
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions